Time to move on to our next virus: Coronavirus. it’s not a super high-yield virus. Not much will get tested about it… Except for a couple of things, which we’ve definitely highlighted in our video. So let’s get started! First, let’s set our scene and cover some basic features. Coronavirus is a positive, single stranded RNA virus So now let’s relate this to our scene. First, corona is latin for “crown”. So naturally we’re going to have to tie it into crowns. by having our scene take place in the countryside of a kingdom. Notice that’s it’s a beautiful sunny day. The daytime setting is to help you remember that this is a positive strand virus because sunny=positive And additionally, the rolling hills are golden yellow A warm color, which tells us that Coronavirus is an RNA virus. Now, we’re going to draw the king up front. With his corona crown Notice, he’s also wearing a thick robe This is to represent that Corona is an encapsulated virus. Also, take note that there’s no naked statue of David in this scene So we’ll actually need to know one little detail about this capsule. And that’s that it’s helical shaped which is somewhat unique to Coronavirus So to cue you in on these helices, we’ll add a long spiraling road that leads up to the kingdom and the road should help you remember that this is a helical virus. We’ve made the trees helical, too, because, why not. So our king is looking pretty ill. So, what does coronavirus actually do? Most people equate coronavirus with SARS but it’s actually important to remember that coronavirus can cause the common cold So we’ve drawn our king sneezing and blowing our nose to help you remember that coronavirus can cause the common cold. Okay, onto the more serious stuff. Different strains of coronavirus can cause SARS and more recently, middle east respiratory syndrome. or MERS, the new kid on the block To help you remember the more serious features of these diseases, we can look at the kings chest. As you can see, this design looks a lot like a respiratory tract that’s all red and inflamed. You can even see that the main bronchi are spreading into bronchial. This helps us remember that coronavirus can cause acute bronchitis That can eventually lead to acute respiratory distress syndrome. You can diagnose SARS with a test for antibodies to SARS or confirm it with PCR Clinically, it’s a negative finding, that there’s an absence of antibodies over 28 days. Treatment can include broad spectrum antibiotics, ribavirin, or corticosteroids. Though the efficacy of any one of those is variable. Our last feature about coronavirus is that it replicates in the cytoplasm. Just like all the other positive sense RNA viruses. Since all of the positive sense RNA viruses replicate in this way, we chose NOT to include it in the sketches, but since this is a short video, I wanted to reinforce it now. So just like the castle is a nucleus to a kingdom, this castle represents a nucleus. And the surrounding fields, the cytoplasm Our coronavirus king is out in the field. So you can remember that coronavirus replicates in the cytoplasm. Well that does it for coronavirus. Not too much to know, but SARS and MERS have been somewhat in the limelight and hopefully now you’ll be equipped to deal with whatever comes your way.

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